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I am thrilled to now be able to offer Daybue to more people living with Rett syndrome, outside of a clinical trial. A calibrated measuring device (eg, oral syringe, oral dosing cup) should be obtained from the pharmacy to measure and deliver the prescribed dose accurately. A calibrated measuring device (eg, oral syringe, oral dosing cup) should be obtained from the pharmacy to measure and deliver the prescribed dose accurately. The most common adverse reactions reported with trofinetide led to statistically significant improvements on the Rett Syndrome Behaviour Questionnaire total score and the Clinical Global Impression-Improvement score at week 12 compared with placebo (coprimary endpoints).

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